While reading the article by Brie Zeltner in The Plain Dealer regarding the discovery by researchers at the Cleveland Clinic, I immediately thought about the potential relationship to multiple sclerosis and the associated cognitive problems.
Evidently, researchers “have identified a brain protein that may play a key role in the memory loss associated with Alzheimer’s disease.“
I flashed back to the extended period of time when my neurologist had me on a once per month regimen of an intravenous infusion of a high dose of Solu-Medrol to “take care of the inflammation.” Is there perhaps a link between MS and the brain protein, known as Neuroligin-1 (NLGN1)? According to the article, this protein “has previously been associated with long-term memory formation.“
My hope is that there is a real potential for investigating the link between this protein and MS. It may be grasping-at-straws but with so little known about the cause of MS, perhaps this potential is worth at least questioning.
Dr. David Brown, chairman of the Clinic’s Anesthesiology Institute and one of the authors of the study said “It might work in many different disease processes that use neuro-inflammation as the central disease feature.” Zeltner reports “Brown believes that targeting microglia inflammation may have even more disease applications than they currently know.“
At any rate, I encourage you to read “Cleveland Clinic Researchers Discover New Brain Protein Linked to Alzheimer’s” on Cleveland.com.